The aims of College of Engineering (CoE) are to nurture hi-tech engineering talent and strengthen research and development. After years of development, the CoE now comprises the Department of Electrical Engineering (EE), Department of Mechanical and Electro-Mechanical Engineering (MEM), Department of Computer Science and Engineering (CSE), Department of Materials and Optoelectronic Science (MOES), Department of Photonics (DOP), Institute of Environmental Engineering (IEE), and Institute of Communications Engineering (ICE). Each department offers bachelor’s, master’s and doctoral programs; however, post-graduate programs are only provided by the institutes. The departments of Electrical Engineering and Mechanical and Electro-Mechanical Engineering recruit about 110 undergraduate students annually. To integrate academic researches in coordination with the Tainan and Kaohsiung Science Parks, the CoE has established a research-oriented center : Engineering Technology Research & Promotion Center. The center is in charge of conducting cooperations with industry and providing technical consultation to fulfill the responsibilities and obligations of National Sun Yat-sen University (NSYSU) for southern Taiwan. 

In 2006, the CoE launched an International Master’s Program in Electrical Power Engineering (IMEPE) in response to an invitation from International Cooperation and Development Fund, Ministry of Foreign Affairs. An International Master’s Program in Telecommunication Engineering (IMPTE) was also established in 2014. All the courses in both International Master’s Programs are taught in English to attract international students all over the world. The CoE offers around 100 English-taught courses each semester. In addition, students are encouraged to take elective English-taught courses offered by other colleges.

The current research areas include Electrical Power and Control, System-on-Chip, Smart Manufacturing, Semiconductor, Micro and Nanosystems, Information Security, Applied Computer Science and AIoT, Inorganic Materials, Polymer Materials and Optoelectronic Science, Photonic Materials and Components, Optical Communication and Optical Information, Display and Alternative Energy, Communication system technology and Radio wave and wireless communication applications, Pollution Prevention, Energy Technology and Environmental Engineering.